Hormones
SHBG test cost — $6.40–$40.95
SHBG · measured in nmol/L
The carrier that decides how much hormone is free.
Optimal windowReference range
An assay-specific reference interval has not yet been added to this guide.
Use the interval printed beside this exact result, including its specimen, units, age/sex group and collection conditions. A range for a similarly named test may not apply.
Optimal range / clinical target
PeptideLab has not verified a separate ‘optimal’ target for this measurement. Reference intervals, diagnostic cutoffs and treatment targets answer different questions.
When SHBG matters
Protocols and goals where this marker is worth tracking.
On TRT, HRT, GLP-1s or peptides? Use the Find tests for your goal tool to see suggested biomarkers and build your monitoring list.
SHBG test prices
Compare direct-pay test prices, without using insurance. Test prices are shown before separate collection fees.
Tracking more than one biomarker?
Build a list to compare test and panel combinations, with one blood-draw fee in your GoodLabs estimate.
$12 blood draw per visit, added once to your order.
Collection fee is additional; not included in this test price.
Does insurance cover SHBG testing?
When a clinician orders SHBG for a diagnosis or to follow a known condition, most plans cover it — and many cover routine screening as $0 preventive care for eligible adults. The catch is you need a qualifying reason and an in-network order; a “I just want to see my number” request often isn’t covered, and if you haven’t met your deductible you can end up paying the lab’s full list price anyway.
The direct-pay prices above skip insurance entirely: you pay the cash price, test on your own schedule with no doctor visit, and it’s HSA/FSA-eligible. For a single marker that’s often cheaper — and faster — than a copay plus deductible exposure.
SHBG inside a bundle
Every compared membership/panel that includes SHBG, cheapest first. Worth it when you want several markers at once rather than a single test.
| Provider | Model | Advertised panel | Price |
|---|---|---|---|
| SiPhox Health | At-home, per-panel (selectable) | 59+ 39 biomarkers mapped | $99-124 / panel |
| Mito Health | At-cost marketplace + optional membership | 100+ 63 biomarkers mapped | Core Panel ~$198 |
| Superpower | Annual membership | 103+ 73 biomarkers mapped | $199/yr |
| Hundred | Annual membership | 160+ 74 biomarkers mapped | $199/yr |
| Function Health | Annual membership | 160+ 88 biomarkers mapped | $365/yr |
| Blueprint (Bryan Johnson) | Annual membership | 160+ 88 biomarkers mapped | $365/yr |
| Life Extension (Elite) | One-time à-la-carte | 45+ 49 biomarkers mapped | ~$449 one-time |
| InsideTracker | Membership + à-la-carte tests | 48+ 46 biomarkers mapped | $489 (1st test) |
| Marek Health | Annual membership | 80+ 55 biomarkers mapped | ~$495/yr |
| OneTwenty | Annual membership | 85+ 51 biomarkers mapped | $499/yr |
| Rythm Health | At-home subscription | 24+ 22 biomarkers mapped | $79/mo |
| Lifeforce | Subscription + diagnostic | 51+ 49 biomarkers mapped | ~$2,137/yr |
What SHBG is
A liver-made protein that binds sex hormones and regulates their bioavailability. It is raised by estrogen, thyroid hormone, and aging, and lowered by insulin resistance, obesity, and androgens.
Why it matters for longevity & performance
SHBG is a metabolic-health marker — low SHBG flags insulin resistance and diabetes risk — and it is essential for correctly interpreting free hormone levels.
SHBG & peptides — what to watch
If you’re running peptides, TRT or HRT, these are the compounds studied in relation to SHBG — useful for deciding what to track. Research associations for monitoring, not medical or dosing advice. Tap one for its full profile.
SHBG testing — frequently asked
Do I need to fast for a SHBG test?
No. SHBG does not require fasting — you can test any time of day.
Do I need a doctor's order to get a SHBG test?
No. Direct-to-consumer labs (GoodLabs, Ulta, Quest and Labcorp OnDemand) include the physician order in the price — you order online and visit a draw site, no appointment with your own doctor needed.
How fast are SHBG results?
Usually 1–3 business days after your blood draw; most results post to the lab's online portal.
What's the difference between the standard and optimal SHBG range?
Reference intervals describe results in a reference population; they do not by themselves diagnose or exclude disease. A treatment target depends on the condition and the person. PeptideLab has not verified a separate ‘optimal’ target for this measurement. Reference intervals, diagnostic cutoffs and treatment targets answer different questions.
Which peptides affect SHBG?
Compounds studied in relation to SHBG include Semaglutide, HGH (Somatropin). These are research associations for monitoring — not medical or dosing advice.
Does insurance cover SHBG testing?
Often, when ordered for a diagnosis; many plans cover it as preventive care at no cost for eligible adults. The direct-pay prices above let you skip insurance and test on your own schedule.
Related Hormones biomarkers
Educational guidance. Use your reporting lab’s reference interval and discuss personal targets and results with your clinician.